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Circulite® Appoints Peter Pfreundschuh as Chief Financial Officer

SADDLE BROOK, N.J. and AACHEN, Germany - 12/02/2008

CircuLite®, Inc. today announced the appointment of Peter Pfreundschuh as Chief Financial Officer. Mr. Pfreundschuh possesses over 15 years of business and financial experience in the life sciences industry. Most recently, he was Executive Director of Business Development and Licensing at AstraZeneca, where he led finance and negotiations in support of new business development opportunities for all external deals and alliances.

“Peter brings to CircuLite extensive experience with operational finance, business development, executing licensing deals, and strategic planning,” said Paul Southworth, President and CEO of CircuLite. “His expertise will be a valuable asset to the company, as we continue our European registration trial for the long-term use of our Synergy™ Micro-pump, pursue CE Mark certification in 2009, and plan to initiate a pilot trial under an IDE in the United States. We welcome Peter to the CircuLite team and look forward to working with him.”

“I am extremely enthusiastic to be joining CircuLite as CFO at this exciting time, and I look forward to working with the team as we plan to obtain CE Mark certification in Europe for the Synergy device,” said Mr. Pfreundschuh. “Synergy has the ability to fulfill a current unmet medical need within the chronic heart failure marketplace, and shows resounding potential value to patients and healthcare providers.”

Prior to joining AstraZeneca, Mr. Pfreundschuh served at Johnson and Johnson as Controller of the R&D division and Controller/Director of Marketing and Global Business Analytics. During this time, he also served as Chief Financial Officer/Treasurer for 3 Dimensional Pharmaceuticals, which was acquired by J&J. Mr. Pfreundschuh has also held management positions at Alimenterics, Inc. and American Standard Companies, Inc., and was a Senior Auditor at Ernst & Young, LLP.

A New Jersey Certified Public Accountant, he holds an MBA with a concentration in finance from Rider University, a BS in accounting from Rutgers University School of Business, and has continued his education through the Executive Strategic Marketing Program in Healthcare at the Kellogg School of Management at Northwestern University.

About Synergy™
The Synergy™ Pocket Micro-pump represents a new approach to mechanical circulatory support that can transform chronic heart failure management by providing a less-invasive, elective treatment option for patients before their disease state becomes emergent. Synergy is the first implantable system designed to provide partial circulatory support (PCS) for long-term use in millions of unserved patients that have NYHA Class IIIb/early IV disease.

CircuLite’s patented micro-pump provides up to 3L/min of flow, which increases total cardiac output, offloads the heart, allowing it to rest, and potentially enables beneficial recovery of heart function. The size of a AA battery, the device is small enough to be implanted subcutaneously in a “pacemaker-like” pocket through a minimally-invasive procedure.

About CircuLite®
CircuLite is transforming heart failure treatment with the development of minimally-invasive devices for long-term partial circulatory support (PCS). By enabling a proactive and lower-risk treatment approach by supplementing a patient’s native pumping capacity, CircuLite has the potential to improve the quality of life for millions of chronic heart failure patients and their families. CircuLite’s pipeline of PCS devices is lead by the Synergy™ Pocket Micro-pump, the world’s smallest implantable blood pump currently in a CE Mark clinical trial. Next-generation Synergy micro-pumps include an endovascular system, a fully-implantable system and a pediatric system. For more information on CircuLite and the Synergy Pocket Micro-pump devices, visit our website at www.CircuLite.net.

Contact
Media:
Kari Watson
MacDougall Biomedical Communications
kwatson@macbiocom.com
(781) 235-3060

CircuLite, Inc.:
Gail Farnan, Vice President, Marketing
(201) 478-7651

Peter Pfreundschuh, Chief Financial Officer
(201) 478-7655

CAUTION: Investigational Device. Limited by Federal Law to Investigational Use Only.

CircuLite® is a registered trademark of CircuLite, Inc. in the United States.
Synergy™ is a trademark of CircuLite, Inc. in the United States.