What is the Synergy Pocket Circulatory Assist (PAC) device?

The Synergy device is currently being developed for the treatment of chronic heart failure patients. The Synergy device features a micro-pump that is designed to pump blood from the Left Atrium to the Subclavian Artery. The Synergy device works together with the patient’s own heart to increase blood flow to the body.

How big is the Synergy Pocket Circulatory Assist (PAC) device?

The Synergy device is the size of an AA battery (measuring approximately ½ inch by 2 inches or 14 mm by 49 mm) and weighs less than an ounce (25g).

Is the Synergy Pocket Circulatory Assist (PAC) device a Ventricular Assist Device (VAD)?

The Synergy device is similar to a VAD, in that it provides circulatory support, but the mode of action and target patient population are different. The Synergy device is implanted into the Left Atrium (instead of the Left Ventricle) and pumps the blood though a superficially placed micro-pump (instead of a pump placed deep in the chest cavity) to the Subclavian Artery (instead of the Aorta). The Synergy device pumps up to 3 liters of blood per minute and supplements the patient’s own native cardiac output. Because of its small size, the Synergy device is designed to be electively implanted in late Class IIIb and early Class IV Heart Failure patients who have exhausted current medical therapy and are experiencing a declining quality of life (instead of the critically ill late Class IV Heart Failure patient who is actually decompensated and is in imminent danger of dying without immediate full support).

How is the Synergy Pocket Circulatory Assist (PAC) device powered?

The Synergy device is connected to a power supply via a percutaneous lead that exits the body in the abdominal area. This percutaneous lead is connected to either two battery packs for mobility or one battery pack and a power supply that is plugged into the wall (i.e., when sleeping).

How can I get the Synergy Pocket Circulatory Assist device implanted?

The Synergy Pocket Circulatory Assist device is not currently approved for human implants. CircuLite is currently conducting a clinical evaluation of the Synergy Pocket Circulatory Assist device in Europe. Please contact us at information@circulite.net if you would like information about the CircuLite trials.

When will the Synergy Pocket Circulatory Assist device be available?

CircuLite is currently conducting a clinical evaluation of the Synergy device in Europe and plans to begin evaluations in the United States in 2008/2009. Commercial product will be available following local approvals.

How can I invest in CircuLite?

CircuLite is a private company, interested investors can contact us at information@circulite.net or +1-201-543-2430 for additional information.

How can I get updates on CircuLite’s progress?

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Where is CircuLite located?