Milestones

Announces ISHLT 2012 data presentations

A total of 50 patients have been implanted with the Synergy device

Awarded private grant to fund the development of a right-heart support system based on Synergy

Closes on Series D Financing with new investor, MacAndrews & Forbes, and Forbion

A total of 42 patients have been implanted with the Synergy device

Closes on Series C Financing

Awarded a fast-track SBIR grant from NIH to fund the development of a pediatric circulatory support device based on Synergy

Presents chronic hemodynamic data for Synergy Micro-pump for chronic heart failure at American College of Cardiology session

Completes initial close on $33 million Series C Financing plan

Attained ISO 13485:2003 Certification

Reports preliminary results of FIM study

Enrolled first patient in European clinical pilot trial

Received site Ethical Committee and Competent Authority approvals to implant (Europe)

Close Series B $25 million Private Placement Funding

Submitted for Ethical Committee approvals for first implants (Europe)

Pre-clinical Studies

Design Freeze Surgical Device

Developed Surgical Implantation Design

Commenced Operations